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Search Results for " gh receptor "

Targets

12

Compounds

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T9692 Paltusotine Somatostatin
Paltusotine is a nonpeptide, small molecule somatostatin type 2 (SST2) receptor agonist with high oral bioavailability. Paltusotine maintains GH and IGF-1 levels in acromegaly patients
TP1155L Human growth hormone-releasing factor acetate GHSR
Human growth hormone-releasing factor acetate is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary[1].
T11798 L-692429 MK-0751 GHSR , GPCR19
L-692429 (MK-0751) is a potent nonpeptidyl growth hormone secretagogue (GHS) agonist, a benzolactam derivative, which reverses the inhibition of GH secretion by glucocorticoids.L-692429 has a high affinity for the G prot...
T7112 Ibutamoren Mesylate MK-0677,MK-677 GHSR
Ibutamoren Mesylate (MK-0677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist.
TP2420 Veldoreotide DG 3173,DG3173,PTR 3173,DG-3173,Somatoprim
Veldoreotide, also known as Somatoprim, is a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue which effectively reduces GH secretion in human GH-secreting pituitary adenomas, even in Octreotide non-r...
T68276 Macimorelin acetate EP-1572 acetate ; AEZS-130 acetate,AEZS-130 acetate,EP-1572 acetate
Macimorelin Acetate (EP-1572), an orally active growth hormone (GH) secretagogue and a ghrelin receptor (GHSR) agonist, stimulates GH release. It is utilized in research focusing on adult growth hormone deficiency (AGHD)...
TP2032 Des-​Gln14-​Ghrelin des-Gln14-Ghrelin (rat)
An endogenous ligand for the ghrelin receptor (GHS-R1a), produced by alternative splicing of the rat ghrelin gene. Potently induces Ca2+ release in cells expressing ghrelin receptors (EC50 = 2.4 nM) and stimulates GH rel...
T75157L Cimdelirsen sodium
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH...
T75157 Cimdelirsen
Cimdelirsen, a novel ligand-conjugated, hepatic-targeted antisense oligonucleotide under investigation, aims to diminish growth hormone receptor (GHr) synthesis. This inhibits the harmful effects of growth hormone (GH) h...
T75713 Human growth hormone-releasing factor TFA
Human Growth Hormone-Releasing Factor TFA, also known as Growth Hormone-Releasing Factor Human TFA, is a hypothalamic polypeptide that promotes the production and release of growth hormone (GH) through its interaction wi...
TP1155 Human growth hormone-releasing factor Growth Hormone Releasing Factor human
Human growth hormone-releasing factor stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary.Growth hormone-releasing hormone is a hormone produced in the hypothal...
TP1532 γ-2-MSH (41-58), amide
Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cel...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-00806 GHR/Growth Hormone R Protein, Human, Recombinant (His) Human HEK293 Cells
Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual f...
TMPJ-00356 GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth,...
TMPH-03682 Varicella-zoster virus (strain Dumas) glycoprotein H/gH Protein (His & Myc) HHV-3 E. coli
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by...
TMPH-03683 Varicella-zoster virus (strain Oka vaccine) glycoprotein H/gH Protein (His) HHV-3 E. coli
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by...
TMPH-03204 GHR Protein, Rabbit, Recombinant (His & Myc) Rabbit E. coli
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormon...
TMPH-03112 GHR Protein, Pig, Recombinant (His) Sus scrofa (Pig) E. coli
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormon...
TMPH-02440 GHR Protein, Rhesus macaque, Recombinant (His) Rhesus E. coli
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormon...
TMPH-01194 Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO) HHV-5 E. coli
Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloi...
TMPY-00186 GHRH Protein, Human, Recombinant (hFc) Human HEK293 Cells
The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of growth hormone (GH) from the pituitary is well established. Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important...
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