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Cat No. | Product Name | Synonyms | Targets |
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T9692 | Paltusotine | Somatostatin | |
Paltusotine is a nonpeptide, small molecule somatostatin type 2 (SST2) receptor agonist with high oral bioavailability. Paltusotine maintains GH and IGF-1 levels in acromegaly patients | |||
TP1155L | Human growth hormone-releasing factor acetate | GHSR | |
Human growth hormone-releasing factor acetate is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary[1]. | |||
T11798 | L-692429 | MK-0751 | GHSR , GPCR19 |
L-692429 (MK-0751) is a potent nonpeptidyl growth hormone secretagogue (GHS) agonist, a benzolactam derivative, which reverses the inhibition of GH secretion by glucocorticoids.L-692429 has a high affinity for the G prot... | |||
T7112 | Ibutamoren Mesylate | MK-0677,MK-677 | GHSR |
Ibutamoren Mesylate (MK-0677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist. | |||
TP2420 | Veldoreotide | DG 3173,DG3173,PTR 3173,DG-3173,Somatoprim | |
Veldoreotide, also known as Somatoprim, is a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue which effectively reduces GH secretion in human GH-secreting pituitary adenomas, even in Octreotide non-r... | |||
T68276 | Macimorelin acetate | EP-1572 acetate ; AEZS-130 acetate,AEZS-130 acetate,EP-1572 acetate | |
Macimorelin Acetate (EP-1572), an orally active growth hormone (GH) secretagogue and a ghrelin receptor (GHSR) agonist, stimulates GH release. It is utilized in research focusing on adult growth hormone deficiency (AGHD)... | |||
TP2032 | Des-Gln14-Ghrelin | des-Gln14-Ghrelin (rat) | |
An endogenous ligand for the ghrelin receptor (GHS-R1a), produced by alternative splicing of the rat ghrelin gene. Potently induces Ca2+ release in cells expressing ghrelin receptors (EC50 = 2.4 nM) and stimulates GH rel... | |||
T75157L | Cimdelirsen sodium | ||
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH... | |||
T75157 | Cimdelirsen | ||
Cimdelirsen, a novel ligand-conjugated, hepatic-targeted antisense oligonucleotide under investigation, aims to diminish growth hormone receptor (GHr) synthesis. This inhibits the harmful effects of growth hormone (GH) h... | |||
T75713 | Human growth hormone-releasing factor TFA | ||
Human Growth Hormone-Releasing Factor TFA, also known as Growth Hormone-Releasing Factor Human TFA, is a hypothalamic polypeptide that promotes the production and release of growth hormone (GH) through its interaction wi... | |||
TP1155 | Human growth hormone-releasing factor | Growth Hormone Releasing Factor human | |
Human growth hormone-releasing factor stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary.Growth hormone-releasing hormone is a hormone produced in the hypothal... | |||
TP1532 | γ-2-MSH (41-58), amide | ||
Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cel... |
Cat No. | Product Name | Species | Expression System |
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TMPK-00806 | GHR/Growth Hormone R Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual f... | |||
TMPJ-00356 | GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth,... | |||
TMPH-03682 | Varicella-zoster virus (strain Dumas) glycoprotein H/gH Protein (His & Myc) | HHV-3 | E. coli |
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by... | |||
TMPH-03683 | Varicella-zoster virus (strain Oka vaccine) glycoprotein H/gH Protein (His) | HHV-3 | E. coli |
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by... | |||
TMPH-03204 | GHR Protein, Rabbit, Recombinant (His & Myc) | Rabbit | E. coli |
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormon... | |||
TMPH-03112 | GHR Protein, Pig, Recombinant (His) | Sus scrofa (Pig) | E. coli |
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormon... | |||
TMPH-02440 | GHR Protein, Rhesus macaque, Recombinant (His) | Rhesus | E. coli |
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormon... | |||
TMPH-01194 | Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO) | HHV-5 | E. coli |
Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloi... | |||
TMPY-00186 | GHRH Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of growth hormone (GH) from the pituitary is well established. Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important... |